Preparation process for making water-soluble lysine salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid
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United States of America Patent
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Jun 9, 1992
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app pub date -
Nov 17, 1989
filing date -
Jan 13, 1988
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Abstract
Water-soluble salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid with DL-lysine, D-lysine or L-lysine, suitable for the preparation of medicinal specialities such as syrups, creams, suppositories, aqueous solutions for personal hygiene etc, and their preparation process. The salts are obtained by suspending said acid in an organic solvent soluble or partly soluble in water, adding an equivalent quantity of the lysine and crystallizing the salt obtained.
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