Nucleic acid process containing improved molecular switch
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United States of America Patent
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Jun 2, 1992
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N/A
app pub date -
Sep 30, 1988
filing date -
Sep 30, 1988
priority date (Note) -
Expired
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Abstract
A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.
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