Method for alkylating guanidino groups
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United States of America Patent
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May 12, 1992
Grant Date -
N/A
app pub date -
Aug 28, 1990
filing date -
Sep 4, 1989
priority date (Note) -
Expired
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Abstract
A method is described for substituting at least one hydrogen atom originally present in the guanidino group of a compound of general formula (I) ##STR1## where R is any substituted or unsubstituted residue, by a group R.sub.1 where R.sub.1 is an unsubstituted or substituted, linear or branched alkyl, consisting of: a) silylating the guanidino group and any other silylatable functional groups present within the R group and b) alkylating the product obtained in step a) with a mixture consisting of the alkyl halide R.sub.1 -X and an organic base containing a tertiary nitrogen.
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