Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
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United States of America Patent
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Apr 14, 1992
Issued Date -
N/A
app pub date -
Oct 7, 1987
filing date -
Jun 29, 1987
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Expired
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Abstract
Monoclonal antibodies capable of binding antigenic determinants within regions of the core proteins of the Human Immunodeficiency Virus and immortalized cell lines producing those monoclonal antibodies are provided. The monoclonal antibodies find use in a variety of ways, including HIV antigen detection in biological samples. Using these methods, individuals may be identified who are infected with HIV but who have not yet developed anti-HIV antibodies. The methods also find use in monitoring in vitro growth of HIV, and the efficacy of therapeutic agents and vaccines.
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