Spiro-dihydroisoindole compounds
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United States of America Patent
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Mar 24, 1992
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N/A
app pub date -
Feb 5, 1991
filing date -
Feb 8, 1990
priority date (Note) -
Expired
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Abstract
The present invention relates to spiroisoindolines that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.
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