Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof
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United States of America Patent
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Feb 18, 1992
Issued Date -
N/A
app pub date -
Dec 18, 1989
filing date -
Dec 22, 1988
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Expired
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Abstract
The present invention relates to a transdermal therapeutical system for the administration of physostigmine to the skin via a cover layer which is impermeable to active substances, a pressure-sensitive adhesive reservoir layer, and optionally a removable protective layer, said reservoir layer consisting of 10-90% polymeric material selected from the groups consisting of block copolymers on the basis of styrene and 1,3-dienes, polyisobutylenes, polymers on the basis of acrylates and/or methacrylates and esters of hydrogenated colophonium, 0-30%-wt softeners on the basis of hydrocarbons and/or esters, and 0.1-20%-wt physostigmine.
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