Monoclonal antibody for use in drug resistant cancers and production thereof
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United States of America Patent
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Feb 11, 1992
Issued Date -
N/A
app pub date -
Oct 1, 1990
filing date -
Sep 11, 1985
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Abstract
Monoclonal antibodies are disclosed that may be produced by hybridomas obtained by fusing a mouse spleen cell immunized with an ADRIAMYCIN.RTM.-resistant human tumor cell and a mouse myeloma cell and which inhibit selectively the growth of cancer cells possessing pleiotropic drug resistance or enhance their sensitivity to said drug.
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