Synthesis of hexahydrolupulone, novel forms thereof, and its use as a selective inhibitor of cell growth and multiplication

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United States of America Patent

PATENT NO 5082975
SERIAL NO

07485996

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Abstract

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A process for making hexahydrolupulone is described which involves the separation of beta acids from a hop extract, the removal of catalyst poisons from the beta acids, the hydrogenation of the beta acids to hexahydrolupulone, and the purification of the resulting hexahydrolupulone. Its use as an inhibitor of the growth of unwanted types of cells is described, as well as preferred forms for such use.

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Patent Owner(s)

Patent OwnerAddress
KALAMAZOO HOLDINGS INC3713 WEST MAIN STREET KALAMAZOO MI 49006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guzinski, James A Kalamazoo, MI 13 287
Todd, Jr Paul H Kalamazoo, MI 29 569

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