End labeled nucleotide probe
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United States of America Patent
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Jan 21, 1992
Grant Date -
N/A
app pub date -
Feb 26, 1988
filing date -
Feb 26, 1988
priority date (Note) -
Expired
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Abstract
An oligo- or polynucleotide having at least one biotin directly or indirectly attached to each of the 5' and 3' end nucleotides thereof and a nucleic acid hybridization assay system for use therewith. The biotins are optionally attached through linkage groups that do not interfere with hybridization. The biotins can further serve to attach a biotinylated polymer.
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