Pyridine derivatives
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United States of America Patent
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Dec 24, 1991
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N/A
app pub date -
Apr 6, 1990
filing date -
Apr 7, 1989
priority date (Note) -
Expired
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Abstract
Pyridine derivatives of formula ##STR1## their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0, 1 and 2 and R, R.sup.1, R.sup.2 and R.sup.2 have specified meanings. The compounds exhibit activity as 5-HT.sub.1A agonists, antagonists or partial agonists and are useful for the treatment of CNS disorders e.g. anxiety, as antihypertensives and in treating anorexia.
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