Microbial susceptibility assay using 7-N-(aminoacyl)-7-amido-4-methylcoumarins

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United States of America Patent

PATENT NO 5064756
SERIAL NO

07540865

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Abstract

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A method of determining the susceptibility of microorganisms to an antimicrobial substance wherein the microorganisms are cultured in the presence of the antimicrobial substance, and growth or lack of growth is assessed by detecting a fluorescent product resulting from the enzymatic hydrolysis of a fluorogenic substrate. The fluorogenic substrates include 7-N-(aminoacyl)-7-amido-4-methylcoumarin, 7-N-(alanyl)-7-amido-4-methylcoumarin, or a combination of 7-N-(alanyl)-7-amido-4-methylcoumarin and 4-methyl umbelliferyl phosphate.

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Patent Owner(s)

Patent OwnerAddress
SIEMENS HEALTHCARE DIAGNOSTICS INC511 BENEDICT AVENUE TARRYTOWN NY 10591

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Badley, Robert A 19 Well Pond Close, Sharnbrook, Bedford, GB3 6 135
Carr, Anthony H 28 Manor Farm Way, Sharnbrook, Bedford, GB3 5 135
Jobling, Ian 25 Lynford Way, Rushden, Northamptonshire, GB3 4 126
Sands, Thomas J 52b Somerford Road, Wellingborough, Northamptonshire, GB3 3 66

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