Imidazolone derivatives with activity on central nervous system and antihypertensive activity, preparation methods thereof, and pharmaceutical compositions containing them

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United States of America Patent

PATENT NO 5059601
SERIAL NO

07467000

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Abstract

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Invention concerns 4,5-bisubstituted-2-imidazolone derivatives of formula I ##STR1## and pharmaceutically acceptable salts thereof, having high affinity in vitro for D.sub.2, 5-HT.sub.2, .sub.1 receptors and in vivo activity on central nervous system and antihypertensive activity with negligible secondary effects; methods for the preparation thereof; pharmaceutical formulations containing them.

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Patent Owner(s)

Patent OwnerAddress
ISTITUTO LUSOFARMACO D'ITALIA S P AVIA CARNIA 26 MILAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cascio, Giuseppe Milan, IT 6 17
Manghisi, Elso Milan, IT 12 70
Salimbeni, Aldo Milan, IT 12 68

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