Expression of human proapolipoprotein A-I
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United States of America Patent
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Oct 22, 1991
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N/A
app pub date -
May 26, 1988
filing date -
May 28, 1987
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Expired
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Abstract
The present invention provides recombinant DNA sequences comprising a sequence which codes for human proapolipoprotein A-I wherein part of the natural coding sequence has been replaced by a DNA fragment coding for the same amino acids but consisting of a different nucleotide sequence such as to reduce or prevent formation of hairpins, cloning and expression vectors containing these DNA sequences, cell cultures or microorganisms transformed with these expression vectors and processes using the same for the production of proapolipoprotein A-I.
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