Peptide derivatives

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United States of America Patent

PATENT NO 5055450
SERIAL NO

07493025

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri- and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out hereinafter, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.

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Patent Owner(s)

Patent OwnerAddress
ZENECA INC1800 CONCORD PIKE WILIMINGTON DE 19897

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Edwards, Philip D Claymont, DE 11 280
Schwartz, John A Wilmington, all, DE 7 136
Stein, Mark M Wilmington, all, DE 8 214
Trainor, Diane A Glen Mills, PA 18 330
Wildonger, Richard A Elmwood, DE 8 238

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