Air cooled cartridge for capillary electrophoresis

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United States of America Patent

PATENT NO 5037523
SERIAL NO

07470209

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An electrophoresis instrument includes a capillary tube mounted in an air cooled cartridge. The cartridge also supports a spherical lens which is part of the optical detection apparatus. The cartridge rests in a manifold which includes the sample and buffer reservoirs. The temperature of the capillary tube is controlled by measuring the electrical resistance of the capillary tube during the electrophoresis process and then cooling or heating the cartridge by circulating temperature controlled air over the tube. The optical path associated with the instrument is a fiber optic bundle bifurcated close to dual detectors into a reference arm and a sample arm so as to provide similar reference and sample optical paths. The instrument may be used for temperature control for gradient electrophoresis and also, a neutral marker for determining electro-osmotic flow may be detected.

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Patent Owner(s)

Patent OwnerAddress
THERMO BIOANALYSIS CORPORATION504 AIRPORT ROAD SANTA FE NM 87504

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hoppe, Thomas W Sparks, NV 3 131
Tarantino, Elia R Sparks, NV 7 612
Weinberger, Scot R Reno, NV 23 703

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