2-thiomethyl-substituted-1,4-dihydropyridines, and pharmaceutical compositions containing same and antihypertensive properties

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United States of America Patent

PATENT NO 5021436
SERIAL NO

07413896

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Abstract

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Compounds of formula I ##STR1## wherein R.sub.1 is an alkoxycarbonyl group, acetyl, benzoyl, cyano, nitro or aminocarbonyl; R.sub.2 is an optionally substituted aryl or hetaryl group; R.sub.3 is an alkoxycarbonyl group; .phi. is a thio residue such as alkylthio, cycloalkylthio, arylthio, heteroarylthio, aminoalkylthio, are described. Compounds I are useful in human therapy as antihypertensive, antiulcer, antithrombotic, antiischaemic agents.

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Patent Owner(s)

  • BOEHRINGER MANNHEIM ITALIA S.P.A.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frigerio, Marco Milan, IT 47 226
Gandolfi, Carmelo A Milan, IT 26 64
Spinelli, Silvano Milan, IT 41 182
Tofanetti, Odoardo Milan, IT 19 65
Tognella, Sengio Milan, IT 1 0

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