Acylated hexahydropyrimidines
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United States of America Patent
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Apr 23, 1991
Issued Date -
N/A
app pub date -
Oct 2, 1990
filing date -
Jun 30, 1989
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Abstract
N'-Acyl-N-alkyl-1,3-diaminopropanes of formula R.sup.1 CONH(CH.sub.2).sub.3 NHR.sup.2 (where R.sup.1 is R- or RNH where R is a substituted or unsubstituted hydrocarbon group and R.sup.2 is alkyl) are prepared by selectively acylating N-alkyl-1,3-diaminopropanes. In the process a N-alkyl-1,3-aminopropane is reacted with an aldehyde to form a hexahydropyrimidine, the hexahydropyrimidine is acylated and the acylated hexahydropyrimidine is then hydrolyzed to give the product.
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