Benzofuran and benzothoiphene derivatives, of tetrazole and anti-hyperuricemia use thereof

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United States of America Patent

PATENT NO 5004750
SERIAL NO

07280564

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Abstract

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A new series of benzofuran and benzothiophene derivatives are disclosed. These compounds have a structure which can be obtained by substituting the third position of 2-lower alkyl-benzofuran or 2-lower alkyl-benzothiophene with a substituted benzene derivative, itaconic acid derivative or a substituted phenoxymethyl tetrazole derivative. They are useful as diuretics without side effects of elevating serum uric acid levels and can be used in the treatment of hyperuricemia.

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Patent Owner(s)

Patent OwnerAddress
KOTOBUKI SEIYAKU COMPANY LIMITEDSAKAKI

International Classification(s)

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  • 1988 Application Filing Year
  • A61K Class
  • 3117 Applications Filed
  • 21 Patents Issued To-Date
  • 0.68 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances1988198919901991199219931994199519961997199819992000200120020255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kubota, Koichi Matsumoto, JP 8 164
Tomiyama, Akira Hanishina, JP 24 159
Tomiyama, Tsuyoshi Hanishina, JP 31 198

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