Pharmaceutical compositions for the inhibition of tumor metastasis
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United States of America Patent
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Apr 2, 1991
Grant Date -
N/A
app pub date -
Jun 29, 1989
filing date -
Jul 13, 1988
priority date (Note) -
Expired
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Abstract
Polyprenols and polyprenyl phosphates are of the formula ##STR1## wherein ##STR2## represents a trans-isoprene unit, ##STR3## represents a cis-isoprene unit, ##STR4## represents a dihydroisoprene unit, l is an integer of 2 to 8, m is 0 or an integer of 5 to 18, n is 0 or 1, the sum of l and m is in the range of 8 to 20, and X represents a hydrogen atom or --PO.sub.3 MM' wherein M and M' may be the same or different and each is a hydrogen atom or a monovalent cation or both M and M' together form a divalent cation. They are useful as a medicament for the inhibition of tumor metastasis.
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