Phosphatidylinositol 4-kinase
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 19, 1991
Grant Date -
N/A
app pub date -
Jun 20, 1988
filing date -
Jun 20, 1988
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A novel phosphatidylinositol 4-kinase isolated from bovine uterus having the following characteristics: (a) molecular weight of about 55 kDa as determined by sodium dodecylsulfate polyacrylamide gel electrophoresis; (b) K.sub.m of about 18 .mu.M for ATP; (c) K.sub.m of about 22 .mu.g/ml for phosphatidylinositol; (d) pH optimum of about 6.0 to 7.0; (e) activated by Mg.sup.2+ ; (f) inhibited by Ca.sup.2+ ; (g) utilizes ATP and 2'-dioxy-ATP as phosphoryl donors and specifically phosphorylates phosphatidylinositol on the 4-position; and (h) essentially free of phosphatidylinositol-4-phosphate 5-kinase activity determined by treatment with phorphoryl donors ADP, GTP, ITP or CTP.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully