Antigens of Leishmania parasites
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United States of America Patent
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Feb 12, 1991
Issued Date -
N/A
app pub date -
Jul 31, 1986
filing date -
Oct 1, 1984
priority date (Note) -
Expired
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Abstract
The invention concerns hybridomes producing anti-Leishmania monoclonal antibodies which are characterized by their capacity to inhibit the infection of sarcomatous cells by the promastigote forms of one or more species of Leishmania, when the sarcomatous cells are placed in contact with the said promastigote forms pre-incubated with these monoclonal antibodies under conditions which, in the absence of the said monoclonal antibodies, would lead to an elevated parasitemia in the said cells. These monoclonal antibodies and the proteins of the parasites that they recognize may be used in the operations of leishmanioses detections.
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