2-selenomethyl-1,4-dihydropyridines having calcium-antagonistic properties and pharmaceutical compositions containing them
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United States of America Patent
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Jan 29, 1991
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N/A
app pub date -
Sep 7, 1989
filing date -
May 29, 1987
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Expired
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Abstract
Compounds of formula I ##STR1## wherein R.sub.1 is a cyano, nitro, acetyl, benzoyl or alkoxycarbonyl group; R.sub.2 is an optionally substituted phenyl or heteroaryl group; R.sub.3 is an alkoxycarbonyl group; R.sub.4 is an alkyl group, optionally substituted by hydroxy, amino, phenyl, heterocyclic group; an optionally substituted phenyl group or an heterocyclic group. Compounds I are useful in human therapy as agents able to interact with CA.sup.++ -dependent systems and as anti-tumor agents.
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