Mannobiose derivatives

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United States of America Patent

PATENT NO 4983725
SERIAL NO

07176329

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Novel mannobiose derivative represented by the general formula [I]: ##STR1## wherein groups of R.sub.1 to R.sub.5 each represents --OH, --OR.sub.6, --NHR.sub.6, (R.sub.6 represents an acyl group) or a group represented by the following formula (a), (b), (c), (d) or (e), provided that one of R.sub.1 to R.sub.5 represents --OR.sub.6 or --NHR.sub.6, one of the other 4 groups of R.sub.1 to R.sub.5 represents one of the groups represented by the formulae (a) to (e), and the remaining 3 groups of R.sub.1 to R.sub.5 represent --OH: ##STR2## wherein represents .alpha. or .beta. bond are provided by the invention. These compounds give liposomes a specific affinity for Kupffer cells of liver, and can be produced industrially.

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Patent Owner(s)

Patent OwnerAddress
MEITO SANGYO CO LTD A CORP OF JAPAN41 SASAZUKA-CHO 2-CHOME NISHI-KU NAGOYA-SHI AICHI-KEN
DAIICHI SEIYAKU CO LTD A CORP OF JAPAN14-10 NIHONBASHI 3-CHOME CHUO-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hirota, Sadao Chigasaki, JP 7 145
Hokukoku, Shusaburo Kani, JP 6 118
Kikuchi, Hiroshi Tokyo, JP 368 4661
Miyaji, Hideki Inazawa, JP 1 6
Tomikawa, Munehiro Chiba, JP 5 50

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