Tissue-affinitive collagen for osteogenesis and method of producing the same
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United States of America Patent
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Dec 4, 1990
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app pub date -
Jun 28, 1989
filing date -
Jun 21, 1985
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Abstract
A good tissue-affinity and lack of antigenicity are required for the collagen used as the carrier of BMP. Conventional collagens have these properties only insufficiently. When the tyrosine content is below 2 residues/1000 residues, then the above properties of such collagens are good. Moreover, collagens excelling in the above properties can be readily obtained by using proteolytic enzymes.
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