Method for purifying L-glutamine
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United States of America Patent
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Oct 30, 1990
Grant Date -
N/A
app pub date -
Jul 11, 1989
filing date -
Jul 11, 1988
priority date (Note) -
Expired
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Abstract
L-glutamine is purified by concentrating a fermentation liquor containing at least 40 g/l or more of L-glutamine, or a solution obtained therefrom by filtering off microbial cells, at pH 5.6.+-.0.5, or by cooling the fermentation liquor or the solution after concentration or without concentration at a temperature in the range of 2.degree. to 30.degree. C., thereby giving a slurry of L-glutamine crystals of 70 g/l or higher concentration; (2) separating the crystals from the mother liquor and then dissolving the separated crystals in a water; and (3) bringing the solution thus obtained into contact with an OH-type anion-exchange resin, thereby removing impurities through adsorption.
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