Optically active benzoquinolizine compounds, process for preparing same, and antibacterial preparation containing same as active ingredient
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United States of America Patent
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Aug 7, 1990
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N/A
app pub date -
Dec 19, 1988
filing date -
Dec 26, 1987
priority date (Note) -
Expired
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Abstract
An optically active (+)-isomer of a benzoquinolizine compound of the formula [I], is provided: ##STR1## where X.sub.1 represents a halogen atom, and R.sub.1 and R.sub.2 represent lower alkyl groups, a physiologically acceptable salt thereof, or a hydrate of either of the foregoing compounds. The compounds [I]-(+) exhibit an excellent antibacterial activity. Also, the compounds exhibit high solubility in water. Therefore, the compounds of the present invention are usable for the treatment of infectious diseases and usable in aqueous liquid preparations such as injections.
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