Optically active azetidinones

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United States of America Patent

PATENT NO 4939248
SERIAL NO

07246826

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides compounds of the formula ##STR1## wherein Y represents an acetyl, 1-hydroxyethyl or 1-fluoroethyl group, R.sub.1 represents a hydrogen atom or an easily splittable amino-protecting group, and R.sub.2 and R.sub.3 are identical or different and each represents a hydrogen atom, a lower alkyl group, a phenyl group, a benzyl group or a diphenylmethyl group, or R.sub.2 and R.sub.3 together represent a lower alkylene group; and processes for production thereof. These compounds are useful as synthesis intermediates for production of various medicines, particulary carbapenam or carbapenem antibiotics, such as a carbapenem antibiotic of the following formula which has excellent antimicrobial activity and relatively good stability to kidney dehydropeptidase. ##STR2##

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Patent Owner(s)

Patent OwnerAddress
SANRAKU INCORPORATEDTOKYO 104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukagawa, Yasuo Kamakura, JP 17 91
Ishikura, Tomoyuki Chigasaki, JP 32 217
Watanabe, Machiko Fujisawa, JP 6 25
Yoshioka, Takeo Ayase, JP 51 280

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