Method for selectively increasing the ratio of single major components of teicoplanin A2 complex
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United States of America Patent
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May 22, 1990
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N/A
app pub date -
May 19, 1986
filing date -
May 21, 1985
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Expired
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Abstract
The object of this invention is to provide a method for selectively increasing the ratio of the single T-A2 major components in the T-A2 complex. More particularly, the object of this invention is a process for obtaining teicoplanin A.sub.2 selectively enriched in any of its major components, T-A2-1, T-A2-2, T-A2-3, T-A2-4 and T-A2-5 which consists in adding to the culture medium of Actinoplanes teichomyceticus nov. sp. ATCC 31121 or a mutant thereof which produces T-A2 complex through the same metabolic pathway, a selectively effective amount of an appropriate precursor.
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