Pharmaceutical preparations
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United States of America Patent
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-
Jan 16, 1990
Grant Date -
N/A
app pub date -
Aug 6, 1987
filing date -
Aug 7, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The synthesis of 4-, 4-(1,1)- and 3,5- substituted N-alkyl-pyridinium salts as well as of 2-carboxamide substituted N(1,4)diazinium compounds are described. The N-surfactants obtained have a small critical micelle concentration (CMC) of 10.sup.-5 -10.sup.-7 Mol/Liter. These surfactants produce micells of different size and form depending on the nature of the anions. 4-(1,1)-substituted and 3,5-substituted N-alkyl-pyridinium components are capable of forming vesicles in equeous solutions of different forms and sizes. The N-surfactants synthesized can be used as pharmaceuticals.
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