Method for determining the turnover of organic material in living tissue and NMR spectrometer for performing this method
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United States of America Patent
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Dec 26, 1989
Grant Date -
N/A
app pub date -
Jun 5, 1987
filing date -
Jun 9, 1986
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Expired
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Abstract
A method for determining the turnover of organic material stored in living organic tissue consists in that the deuterium content of the stored material is artificially modified from natural abundance and monitored as a function of time by measuring the CHD-signal by means of magnetic resonance spectroscopy. E.g., for determining the fat turnover in living beings, the deuterium content of the body fat may be increased by administering to the living being drinking water contaiing 10% D.sub.2 O for 28 days. Thereafter, the decrease of the deuterium content of the body fat is monitored while normal water is administered. The loss of .sup.2 H from body fat is an indication for the body fat turnover.
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