Derivatives from cervinomycin based antibiotics
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United States of America Patent
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Dec 12, 1989
Grant Date -
N/A
app pub date -
Oct 19, 1987
filing date -
Feb 17, 1986
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention is to provide a novel cervinomycin derivative represented by formula ##STR1## wherein ring B represents ##STR2## at least one of R.sub.1, R.sub.2 and R.sub.3 represents an acyl group or an alkyl group and the others represent a hydrogen atom; and R.sub.4 is a hydrogen atom or an alkyl group, and a process for producing said derivatives. The present derivative is free from the problems of the conventional cervinomycin, i.e., the low solubility in various solvents, high toxicity, and low activity against Gram-positive bacteria.
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