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United States of America Patent

PATENT NO 4870172
SERIAL NO

07074369

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Abstract

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A novel compound having anti-tumor activity is disclosed which is 1,12-dihydroxy-1,6,12,17-tetraazacyclodocosan-2,5,13,16-tetrone produced microbiologically by culturing a microorganism belonging to the genus of Alteromonas or, in particular, Alteromonas haloplanktis SB-1123. The characterization data of the compound and the microbiological properties of the microorganism are described. The results of in vitro assays are given for the anti-tumor activity of the compound against L-1210 and IMC carcinoma cells.

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  • MICROBIAL CHEMISTRY RESEARCH FOUNDATION

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Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances1987198819891990199119921993199419950255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ishizuka, Masaaki Tokyo, JP 31 115
Kamayama, Toshiyuki Tokyo, JP 1 7
Kurasawa, Shogo Tokyo, JP 1 7
Okami, Yoshiro Tokyo, JP 12 67
Takahashi, Atsushi Kawasaki, JP 443 3708
Umezawa, deceased Hamao late of Tokyo, JP 10 28

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