Galenic formulations for oral use of rhein derivatives with delayed release for therapeutical use
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United States of America Patent
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Aug 29, 1989
Grant Date -
N/A
app pub date -
Sep 30, 1987
filing date -
Oct 1, 1986
priority date (Note) -
Expired
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Abstract
Several methods are disclosed for the preparation of oral pharmaceutical forms with delayed release of rhein and its derivatives. The pharmaceutically active ingredient is provided in the form of granules, coated with at least one of polyvinylpyrrolidone, shellac and hydroxypropylmethyl cellulose. The desired effect of the coating is to slow release of the pharmaceutically active ingredient by resisting gastric juices in the stomach, but gradually dissolving in the intestines.
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