Pure enantiomers of 4,5-disubstituted gamma-butyrolactams, and their use as antiamnestic agents
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United States of America Patent
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Jul 11, 1989
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N/A
app pub date -
May 14, 1987
filing date -
May 21, 1986
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Expired
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Abstract
The invention provides pure enatiomers of 4,5-disubstituted .gamma.-butyrolactams of the general formula ##STR1## By means of the pure enantiomers of 4,5-disubstituted .gamma.-butyrolactams (I), according to the invention, it is now possible to synthesize (+)-(3R), (4S), (5S), (7R)-3-hydroxy-5-.alpha.-hydroxybenzyl-1-methyl-4-phenyl-pyrrolidin-2-one and derivatives in the form of pure enantiomers.
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