Calcification mitigation of implantable bioprostheses
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United States of America Patent
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Jun 13, 1989
Grant Date -
N/A
app pub date -
Apr 17, 1987
filing date -
Apr 17, 1987
priority date (Note) -
Expired
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Abstract
A process for treating biological tissue prior to implantation to mitigate the calcification of the tissue following implantation comprises incorporating acetylsalicylic acid into the tissue in an amount effective to reduce calcification of the tissue after it is implanted. In accordance with one embodiment, the process involves convalently binding the acetylsalicylic acid to the tissue via a coupling agent.
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