Novel controlled release formulations of tetracycline compounds
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United States of America Patent
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Jun 6, 1989
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N/A
app pub date -
Oct 6, 1987
filing date -
Oct 6, 1987
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Expired
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Abstract
Pharmaceutical compositions comprising spherical granules including thereon or therein a 7- or 9-akylamino-6-deoxy-6-demethyltetracycline or an acid-addition salt thereof blended with at least one excipient are adapted to control the rate of drug release in the stomach and in the intenstine in order not to produce nausea or dizziness upon oral administration during antibacterial therapy.
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