Peptide composition as anitgen for detection of antibodies to HTLV-I, as a vaccine for ATL and methods therefor

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United States of America Patent

PATENT NO 4833071
SERIAL NO

07001885

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Abstract

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The present invention relates to a method for the detection and diagonosis of ATL (adult T cell leukemia/lypmphoma) condition by the use of chemically synthesized peptide composition. The peptide composition comprises peptides having amino acid sequences corresponding to segments of the envelope protein, p21, of HTLV-I and mixtures thereof. The peptide composition is highly immunoreactive with antibodies in sera of patients with ATL. The detection method includes an enzyme-linked immunosorbent assey (ELISA), an immunoradiometric assay (IRMA), and other forms of immunoassay procedures such as enzyme immuno blotting assay on nitrocellulose paper and hemagglutination assay using the peptide composition as the antigen. The preferred detection method is ELISA.

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Patent Owner(s)

Patent OwnerAddress
UNITED BIOMEDICAL INC A CORP OF DE2 NEVADA DRIVE LAKE SUCCESS NY 11041

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Walters, D Wayne Mineola, NY 1 28
Wang, Chang Y Great Neck, NY 7 228
Wang, James J G Flushing, NY 4 110

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