6-amino-2-naphthyl 4-gusnichinobenzoate derivatives and pharmaceutical composition containing them

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United States of America Patent

PATENT NO 4820730
SERIAL NO

07217405

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Abstract

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Amidine compounds of formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin, anti-plasmin, anti-kallikrein, anti-thrombin and anti-complement agents which may be administered orally. These amidine compounds can be produced by the reaction between a carboxylic acid compound of formula (II) ##STR2## or a reactive intermediate thereof and 6-amidino-2-naphthol of formula (III) ##STR3## or preferably an acid addition salt thereof.

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Patent Owner(s)

Patent OwnerAddress
TORII & CO LTD3-14 NIHONBASHI-HONCHO-3-CHOME CHUO-KU A CORP OF JAPAN TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoyama, Takuo Sakura, JP 6 77
Fujii, Setsurou Kyoto, JP 2 6
Kurumi, Masateru Narita, JP 7 130
Nakayama, Toyoo Funabashi, JP 13 188
Nunomura, Shigeki Chiba, JP 14 164
Okutome, Toshiyuki Tokyo, JP 11 178
Sudo, Kimio Chiba, JP 10 81
Watanabe, Shinichi Otsu, JP 98 1961

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