Physically modified beclomethasone dipropionate suitable for use in aerosols
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United States of America Patent
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Mar 7, 1989
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N/A
app pub date -
Aug 18, 1986
filing date -
Dec 19, 1984
priority date (Note) -
Expired
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Abstract
A method for preparing a stable aerosol formulation of beclomethasone dipropionate in which the steroid is contacted with an alcohol containing 1 to 5 carbon atoms to form a crystalline solvate therewith, the crystalline material so formed being reduced to a particle size below 10 microns and thereafter dispersed in a composition comprising chlorofluorocarbon propellents.
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