Aminoalkoxy or carboxyalkoxy derivatives of propranolol for immunoassay applications
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United States of America Patent
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Jan 3, 1989
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N/A
app pub date -
Oct 3, 1986
filing date -
Apr 15, 1982
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Expired
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Abstract
Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4',5',6',7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.
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