Tritium labelled N-mustard type compounds and a process for their production

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United States of America Patent

PATENT NO 4795627
SERIAL NO

06662276

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Abstract

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The present invention describes novel tritium labelled nitrogen mustard type compounds, and their aziridinium type analog, and a process for the production of same. The compounds are of value in medical research and development and also as active ingredients of pharmaceutical compositions. The compounds can be used to develop analogs of human disease states and can also be used to evaluate the mechanism of neurotransmitter regulation and function, both in vitro and in vivo.

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Patent OwnerAddress
PITTSBURGH UNIVERSITY OF5TH AVENUE AND BIGELOW BOULEVARD PITTSBURGH PA 15260
STATE OF ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCHPO BOX 19 PRIME MINISTERS OFFICE NESS-ZIONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abraham, Donald J Murrysville, PA 35 806
Fisher, Abraham Holon, IL 43 598
Hanin, Israel Pittsburgh, PA 3 60

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