Cephalosporin derivatives

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United States of America Patent

PATENT NO 4785090
SERIAL NO

06704077

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This is a class of antibacterial compounds of the formula: ##STR1## wherein Y is straight or branched alkyl or alkenyl chain, cycloalkanomethyl of 3-6 carbon atoms, each group being optionally substituted by halogen, or a group ##STR2## wherein n is 0 or an integer of 1-3, A is a group --COR.sup.3 wherein R.sup.3 is hydroxy, a group ##STR3## wherein R.sup.4 and R.sup.5, which may be the same or different, are hydrogen or alkyl of 1-5 carbon atoms, a group ##STR4## or a 5- or 6-membered heterocyclic group containing nitrogen and/or sulfur, and R.sup.1 and R.sup.2, which may be the same or different, are hydrogen, alkyl of 1-5 carbon atoms, or R.sup.1 and R.sup.2 may be combined together to form cycloalkylidene of 3-5 carbon atoms, and Z is a group of the formula: ##STR5## wherein m is 0 or an integer of 3-5, R.sup.6 is hydrogen or alkyl of 1-3 carbon atoms, and R.sup.7, when m is an integer of 3-5, is alkyl of 1-5 carbon atoms, alkenyl, cyclopropyl, a group --(CH.sub.2).sub.p B wherein p is 0 or an integer of 1-3 and B is amino, alkyl-substituted amino, hydroxy, carboxy, carbamoyl, trifluoromethyl, sulfonic acid, sulfonic acid amide, alkylthio or cyano or, when m is 0, is alkyl of 1-5 carbon atoms, which may optionally be substituted by halogen, alkenyl, a group ##STR6## wherein R.sup.8 is hydrogen, alkyl of 1-4 carbon atoms or phenyl, or cyclopropyl, and a salt thereof.

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Patent Owner(s)

Patent OwnerAddress
MITSUHASHI SUSUMU35-11 NISHIKUBO 1-CHOME MUSASHINO-SHI TOKYO

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fukatsu, Shunzo Tokyo, JP 30 132
Inoue, Shigeharu Yokohama, JP 7 76
Iwamatsu, Katsuyoshi Yokohama, JP 29 99
Katano, Kiyoaki Yokohama, JP 24 129
Kondo, Shinichi Yokohama, JP 165 1091
Murai, Yasushi Yokosuka, JP 39 235
Nakabayashi, Satoru Kawasaki, JP 10 89
Ogino, Hiroko Kawasaki, JP 12 92
Okonogi, Tsuneo Yokohama, JP 17 97
Shibahara, Seiji Machida, JP 79 707
Tsuruoka, Takashi Kawasaki, JP 44 325
Yoshida, Takashi Tokyo, JP 455 5434

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