Expression and diagnostic use of pENV-3 encoded peptides which are immunologically reactive with antibodies to LAV
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Nov 15, 1988
Issued Date -
N/A
app pub date -
Oct 2, 1985
filing date -
Apr 8, 1985
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
A method of expressing peptides which are immunologically reactive with antibodies to LAV is disclosed. The peptides are produced by bacterial host cells transformed with a recombinant plasmid which includes appropriate procaryotic transcriptional and translational signals for expression, followed by a DNA sequence coding for a peptide comprising the amino acid sequence as shown in FIG. 5 starting with isoleucine, number 1, and ending with threonine, number 173. The peptides of the present invention are immunologically reactive with antibodies to LAV, or antibodies to viruses defined to be the same as or equivalent to LAV. The peptides produced by the method disclosed may be used to screen for the presence of antibodies to LAV in a biological fluid, to determine the presence of LAV antigen in a biological fluid, or within a method for producing antibodies to LAV through the immunization of an animal with the peptide. Further, the pNEV-3 encoded peptides may be used as a vaccine against infection by the causative virus for acquired immune deficiency syndrome.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully