Diazonium compounds useful as components for nucleic acid probes
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United States of America Patent
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Oct 4, 1988
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N/A
app pub date -
Dec 8, 1986
filing date -
Dec 8, 1986
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Expired
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Abstract
This invention relates to a diazonium compound of the formula: ##STR1## wherein Z is selected from the group consisting of biotin, an antigen, an antibody, a photoreactive group, a fluorescent group and heavy metal-containing compounds; X is an alkylene group containing up to 18 carbon atoms in the principle chain and a total of up to 24 carbon atoms or a substituted alkylene group containing up to 18 carbon atoms in the principle chain with substituents selected from the group consisting of solubility-enhancing groups and cleavable --S--S-- containing moieties; Ar is an unsubstituted or substituted aryl or heteroaryl; and Y is an anion and n is an integer from 1-3. Such compounds are useful as components for nucleic acid probes.
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