Intermediate compounds for the preparation of antibacterial penem derivatives
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United States of America Patent
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Sep 20, 1988
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Apr 22, 1986
filing date -
Jul 8, 1981
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Abstract
Intermediate compounds of the formula ##STR1## for the preparation of antibacterially active penem compounds and salts wherein R is hydrogen or an esterifying group, R.sup.1 is an unsubstituted or a mono-, di-, or tri-substituted phenyl, naphthyl, thienyl, pyridyl, quinolyl or isoquinolyl, R.sup.2 is hydrogen or a hydroxyl group which may be protected, R.sup.4 is chlorine or bromine and R.sup.5 is an alkyl or phenyl group; methods for making such compounds or salts.
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