Hirudin-PA and its derivatives, process for manufacturing these and the use of these substances
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United States of America Patent
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Aug 30, 1988
Grant Date -
N/A
app pub date -
Aug 6, 1986
filing date -
Dec 13, 1984
priority date (Note) -
Expired
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Abstract
The present invention relates to a new content substance found in leeches (Hirudo medicinalis), the derivatives of this abbreviated at the N-terminus and the C-terminus, and the desulfated derivatives therefrom as well as a process for the production of these compounds, and their use. These compounds possess thrombin-inhibiting properties and can be used to inhibit clotting in human and animals, for blood conservation, or as reagents for the analytical determination of thrombin.
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