Propenylamines, pharmaceutical compositions containing them and their use as pharmaceuticals
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United States of America Patent
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Jul 5, 1988
Issued Date -
N/A
app pub date -
Sep 4, 1984
filing date -
Aug 22, 1979
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A compound of the formula: ##STR1## wherein the double bond is in the trans configuration and R.sub.1 is a radical of formula IIa, ##STR2## R.sub.2, R.sub.3, R.sub.5, R.sub.7 and R.sub.8 are each hydrogen, R.sub.4 is methyl, and R.sub.6 is a radical of formula IIIa --C.tbd.C--R.sub.11 IIIa where R.sub.11 is n-butyl, tertiary butyl or phenyl or a chemotherapeutically acceptable acid addition salt thereof; processes for their production, their use as pharmaceuticals and pharmaceutical compositions containing them.
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