Quinazoline derivative and anti-hypertensive agents
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United States of America Patent
Stats
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Jun 7, 1988
Grant Date -
N/A
app pub date -
Feb 13, 1987
filing date -
Mar 13, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
New quinazoline derivatives are disclosed, as represented by the following formula: ##STR1## wherein A is hydrogen atom or lower alkyloxy group; R.sub.4 is hydrogen atom, a lower alkyl, lower alkyloxy or a halogen atom group. Y is hydrogen atom, lower alkyloxy, sulfamoyl or Y and R.sub.4, taken together, are joined to form --O--CH.sub.2 --CH.sub.2 --O--; Z is a 4-oxopiperidino, 4-thioxopiperidino, 4-oximepiperidino, 4-O-loweralkyl-oxime-piperidino, 4-O-(3-lower alkyl-2-hydroxypropyl)-oxime-piperidino, 4-O-(3-lower alkylamino-2-hydroxypropyl)-oxime-piperidino or 4-O-(3-N'-lower alkyl, N'-benzylamino-2-hydroxypropyl)-oxime-piperidino group. These compounds are useful as anti-hypertensive agents.
First Claim
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Patent Citation Ranking
- 2 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 37 Age