Disease diagnosis by detection of shed normal tissue antigens
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United States of America Patent
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Mar 15, 1988
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N/A
app pub date -
Jun 4, 1984
filing date -
Jun 4, 1984
priority date (Note) -
Expired
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Abstract
Methods are provided for the detection of proximal convoluted tubule causing diseases or kidney harmful drug monitoring by detecting the presence of shed normal proximal tubule associated antigens in a body fluid such as urine. The preferred embodiment employs an ELISA sandwich format wherein one monoclonal antibody specific for a first epitopic site on said antigen is immobilized on a solid phase and a second antibody, specific for a second epitopic site on said antigen is directly or indirectly labeled.
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