Carbacyclin derivatives, method of manufacturing the same and therapeutic agents containing these compounds
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United States of America Patent
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Mar 8, 1988
Grant Date -
N/A
app pub date -
Jun 1, 1987
filing date -
Jul 8, 1986
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
New agents of carbacyclin derivatives are disclosed, which are represented by the following formula: ##STR1## wherein A is a --CH.dbd.CH-- or --C.tbd.C-- group. B is a substituted or unsubstituted indanyl group, substituted or unsubstituted benzodioxanyl group, substituted or unsubstituted benzodioxolanyl group or 2,3,5,6,7, 8-hexahydrobenzodioxanyl group. D is --CH.sub.2 -- or --O--. .about.OH group represents .alpha. or .beta. configuration of OH group; and ##STR2## These compounds are useful as anit-ulcer, anti-hypertensive or anti-thrombotic agents.
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